Therapeutic Nanoparticles and Their Targeted Delivery Applications

Biofunctionalized targeted nanoparticles for therapeutic applications.

BACKGROUND The development of nanoparticles for the delivery of therapeutic agents has introduced new opportunities for the improvement of medical treatment. Recent efforts have focused on developing targeted nanoparticles, which are formulated by (for therapeutic delivery) functionalizing nanoparticle surfaces with targeting molecules, such as antibodies, peptides, small molecules and oligonuc...

Nanoparticles and their Therapeutic Applications in Pharmacy

Nanotechnology is providing solutions several pharmaceutical drug delivery issues. With the emergence of nanotechnology, researchers become more interested in studying the unique properties of nanoscale materials. Nanoparticles are attractive tool in pharmaceutical and biomedical fields. These particulate systems have been used as a physical approach to alter and improve the pharmacokinetic and...

Virus‐like particles: Next‐generation nanoparticles for targeted therapeutic delivery

Most drug therapies distribute the agents throughout the entire body, even though the drugs are typically only needed at specific tissues. This often limits dosage and causes discomfort and harmful side-effects. Significant research has examined nanoparticles (NPs) for use as targeted delivery vehicles for therapeutic cargo, however, major clinical success has been limited. Current work focuses...

Targeted drug delivery to magnetic implants for therapeutic applications

A new method for locally targeted drug delivery is proposed that employs magnetic implants placed directly in the cardiovascular system to attract injected magnetic carriers. Theoretical simulations and experimental results support the assumption that using magnetic implants in combination with externally applied magnetic field will optimize the delivery of magnetic drug to selected sites withi...

Pullulan-based nanoparticles: future therapeutic applications in transmucosal protein delivery.